Florida’s surgeon general announced Wednesday that the state will move to end all vaccine mandates, a step that would make Florida the first state to withdraw from the practice and would remove requirements that children be vaccinated to attend school.

Surgeon General Joseph Ladapo, a vocal critic of mainstream vaccine guidance, likened vaccine mandates to slavery and asked, "Who am I to tell you what your child should put in their body?" Governor Ron DeSantis endorsed the move but said it would take "changes from the legislature" to eliminate mandates entirely.

Officials said the change would affect immunization requirements that have long been used to control the spread of infectious diseases in schools and other settings. Public health authorities and researchers have credited vaccine mandates with increasing vaccination rates and lowering the risk that diseases such as measles will spread in communities.

Ladapo, who has repeatedly challenged mainstream scientific positions on vaccines, has in the past downplayed the importance of COVID-19 vaccines and described them as "nothing special," according to public records and previous statements. He has also promoted treatments such as hydroxychloroquine for COVID-19; the World Health Organization has warned that hydroxychloroquine is not an effective treatment for the virus.

The surgeon general’s announcement did not include an immediate timetable for changes or a detailed plan for how existing mandates would be rescinded. DeSantis’ acknowledgment that legislative changes are necessary indicates the initiative will require action by Florida lawmakers before mandates can be removed statewide.

Public health experts have warned that rolling back vaccine requirements could leave communities more vulnerable to outbreaks of preventable diseases. Mandatory immunization policies have been a longtime public health tool to achieve and maintain high levels of vaccination, particularly among school-aged children, and have been associated with reductions in the incidence of diseases preventable by vaccines.

Supporters of removing mandates argue the decision enhances individual medical freedom and parental choice. Opponents say rescinding requirements risks lowering vaccination coverage and reversing public health gains that reduced rates of serious infectious diseases.

If enacted, Florida’s move would represent an unprecedented statewide reversal in the United States, where vaccine requirements for school attendance are common and have been linked to improved public health outcomes. The outcome will depend on how the state legislature responds to the governor’s and surgeon general’s proposals and on potential legal and administrative challenges that could arise as state policies are changed.

The announcement adds Florida to a national debate over personal liberty, parental rights and public health policy that intensified during the COVID-19 pandemic. Federal and state public health authorities continue to recommend vaccines as a key tool to prevent illness and save lives, and many health officials emphasize the role of vaccination mandates in protecting populations that cannot be vaccinated for medical reasons.

Lawmakers, school officials and public health leaders in Florida and beyond are likely to weigh in as the process unfolds, including on the timing of any repeal, which kinds of mandates would be affected and how exemptions would be handled. For now, the plan announced Wednesday signals a concerted push by state leadership to curtail one of the long-standing mechanisms used to maintain high vaccination coverage in schools and other institutions.