Errol Spence Jr. is set to return to the boxing ring after a three-year absence to face Tim Tszyu in Australia. The fight marks Spence's first bout since suffering the only loss of his professional career.

Three years ago, Spence was defeated by TKO in a highly anticipated match against Terence Crawford. Now, the former welterweight champion faces the challenge of competing against Tszyu in Australia, just outside of Sydney, in his comeback fight.

Several factors could influence Spence's performance. In addition to his extended layoff, he has also changed trainers since his last fight. Furthermore, Spence has limited experience fighting outside the United States, having competed only twice internationally in Canada and the United Kingdom. Tszyu, conversely, will benefit from fighting in front of his home crowd.

Despite these variables, Spence remains the favorite. Prior to his loss to Crawford, he was a dominant force in the welterweight division, known for his aggressive style and finishing power. His southpaw stance is also considered an advantage, as evidenced by Tszyu's previous loss to another southpaw, Sebastian Fundora, who effectively used pressure to keep Tszyu off balance.

Spence has indicated that this fight could be his last, regardless of the outcome, suggesting a strong motivation to leave his career on a positive note and move past the memory of his defeat to Crawford. While the decision to retire remains his own, analysts anticipate his victory in the upcoming bout. Mylik Smith, a sports betting industry expert since 2017 with a focus on combat sports, identified Spence on the moneyline (-140 at DraftKings) as a recommended bet for the match.