Christina Applegate's daughter, Sadie Grace LeNoble, greeted her mother with a spirited welcome home sign after a four-month hospitalization. Applegate shared a photo on Instagram of the garland arranged by her 15-year-old daughter, which read, "You’re home. Happy day, ho."

Applegate, 54, captioned the post, "My kid is so my kid hahaha," noting that she meant to share the moment earlier. The actress was discharged from the hospital in early August. She has been publicly navigating her multiple sclerosis (MS) diagnosis, which she revealed in 2021.

In March, Applegate was hospitalized in Los Angeles. At the time, it was unclear if her admission was related to her autoimmune condition. A representative for Applegate stated to Page Six that they would not comment on her medical treatments, but acknowledged her history of health issues. In April, Applegate shared an update on Instagram, assuring fans she was "getting stronger and better every day" and thanking them for their support. She also mentioned that her health struggles are ongoing but that she would share more when she was ready.

During her hospitalization, reports indicated that those close to Applegate were concerned about her condition, describing her hospital stay as "hellish." A source told the Daily Mail that while Applegate is a fighter, her MS battle has been difficult, with a mix of better and bad days. The source also highlighted the strong support system of friends surrounding her.

Applegate first disclosed her MS diagnosis in August 2021, describing her journey with the condition as "strange" and "tough." She has since spoken about how her battle with MS has impacted her daughter, Sadie. Applegate shared that Sadie witnesses her mother's struggles, such as days when her legs don't work, but noted that her daughter has consistently supported her throughout her health challenges.

Applegate shares Sadie with her husband, musician Martyn LeNoble. The actress has been open about her health journey, including her MS diagnosis, and has continued to share updates with her fans.