Colombia enters the final Round of 32 World Cup match as the favorite against Ghana, who finished second in Group L. The match, scheduled for Friday night in Kansas City, marks the first-ever encounter between the two nations.

Colombia, undefeated in group play with a 2-0-1 record, defeated Uzbekistan and DR Congo before drawing with Portugal. Their attack, led by Luis Diaz and Daniel Munoz, is noted for its speed, while their defense has conceded only one goal in the tournament. Colombia's offense has recorded 19 shots on goal across three matches, averaging 6.3 per game.

Ghana, meanwhile, secured their spot in the knockout stage after finishing third in Group L. After a 1-0 win over Panama, Ghana played England to a scoreless draw, and then fell 2-1 to Croatia in a match where key starters were rested. The Black Stars' offense has struggled, generating only three significant chances in their group matches, with their sole goal coming late in stoppage time in their opener. The team relies heavily on high-pressing and solid defending.

Colombia is a significant favorite to advance, listed at -425 to move on to the Round of 16 and -190 to win within 90 minutes. Ghana faces longer odds, with +310 to advance and +575 on the moneyline. Betting predictions suggest Colombia to win and the total goals to be under 3.5.

Colombia's experienced front three, including Diaz, James Rodriguez, and Luis Suarez, are expected to manage possession and control the attacking play. Despite Ghana's physicality and resilient defense, Colombia is anticipated to maintain their form and advance. The Ghanaian coaching staff faces decisions on their starting goalkeeper between Lawrence Ati Zigi and Benjamin Asare due to injury concerns.