The San Francisco 49ers are scheduled to face the Los Angeles Chargers in a preseason matchup on Thursday night, with both teams grappling with significant injury concerns that may limit the playing time of key personnel.
San Francisco has been particularly impacted by injuries during training camp. Coach Kyle Shanahan indicated there is a "good chance" quarterback Brock Purdy will participate in the game, which serves as a final dress rehearsal before the regular season begins. Purdy threw for 13 points in a previous contest, and with starters expected to see limited action, the team aims to protect its players.
For the Chargers, coach Jim Harbaugh anticipates Justin Herbert will play briefly in the first quarter. However, the team will be without starting center Tyler Biadasz, who recently tore his ACL. Trey Lance is expected to take over for Herbert at some point during the game. Lance is competing for the backup quarterback position with DJ Uiagalelei. The matchup also presents a potential opportunity for Lance, who previously played for the 49ers after being selected third overall in the NFL draft.
Given the widespread injuries affecting both rosters, the betting consensus targets an under 38.5 total points for the contest, with odds at -110 on BetMGM.