Trey Mancini has announced his retirement from professional baseball, concluding an eight-year Major League Baseball career. Mancini shared the news Tuesday via an Instagram post, marking the end of a journey that included two notable returns to the big leagues.
Mancini expressed gratitude for his time with several organizations, notably the Baltimore Orioles, where he spent the majority of his career. During his six seasons with the Orioles, he hit 117 home runs and finished third in the American League Rookie of the Year voting in 2017. He also thanked the Houston Astros for the opportunity to win a World Series and acknowledged the Chicago Cubs, Los Angeles Angels, Cincinnati Reds, Miami Marlins, and Arizona Diamondbacks for providing him with opportunities.
"To every fan, especially those in Birdland, your support over the years has meant the world to me," Mancini wrote in his post. "There is nothing more special in sports than a connection between a team and their fans, and I was lucky enough to feel that everywhere I played."
A Battle With Cancer
Mancini's career path included a significant health battle. In 2020, he missed the entire season after being diagnosed with Stage 3 colon cancer, which required surgery and chemotherapy. He made a remarkable comeback in 2021, playing 147 games for the Orioles and hitting 21 home runs, earning him the AL Comeback Player of the Year award.
Career Highlights
A year after his comeback, Mancini was traded to the Houston Astros and was part of the team that won the World Series in 2022. He also spent time in Triple-A in 2025 and signed a minor league deal with the Los Angeles Angels earlier this year, earning a call-up in June. He recorded three hits in his first game back with the Angels but was designated for assignment after five contests.
"It was fun to be back out there," Mancini said at the time of his most recent return. "It's the same emotions you go through when you debut when it's been that long of a layoff. It was just great to be back out there and something I definitely don't — and won't — take for granted." Mancini, 34, also thanked his wife, Sara, his family, friends, teammates, and coaches in his retirement announcement.