College football returns this week with Week 0 matchups, including North Carolina versus TCU and San Jose State against USC. The slate offers early-season betting opportunities, with analyses focusing on team performance, key players, and potential outcomes.

North Carolina vs. TCU

The North Carolina Tar Heels, under first-year head coach Bill Belichick, are looking to rebound from a disappointing 4-8 record last season. Their 2025 campaign began with a significant loss to TCU, 48-14. The team's limited wins last year were not particularly dominant, indicating a challenging rebuilding process ahead.

TCU enters the season with optimism surrounding quarterback Jaden Craig, a transfer from Harvard. Jeremy Payne is expected to be the featured running back. Last season, TCU secured a bowl victory over USC in overtime, 30-27. Betting analysis suggests TCU's team total over 27.5 points is a strong possibility, with expectations of consistent scoring against a North Carolina defense anticipated to struggle.

San Jose State vs. USC

USC faces San Jose State in a game expected to be heavily lopsided. USC has dominated past matchups, outscoring San Jose State 146-38 over their last three meetings. San Jose State finished 3-9 last season and failed to qualify for a bowl game.

USC, ranked 14th nationally, aims for its first College Football Playoff appearance. Quarterback Jayden Maiava returns after a strong 2025 season, throwing for 3,711 yards and 24 touchdowns. Running back King Miller is also back to lead the offensive backfield, though the team lost a key receiver to the NFL. Despite expectations of a large victory margin, betting predictions lean towards the USC team total falling under 50.5, with an additional prop bet favoring Miller to score two or more touchdowns.

Bill Belichick looks on field