The Arizona Cardinals will commence their 2026 season against the Los Angeles Chargers on Sunday, September 13, at SoFi Stadium in Inglewood, California. The game is scheduled to begin at 4:25 p.m. ET.
The Chargers are favored by 8.5 points in the matchup, according to oddsmakers, citing the team's new offensive coordinator, a healthy tackle duo of Rashawn Slater and Joe Alt, and a new system. This marks the beginning of what is referred to as the "Herbert-Harbaugh-McDaniel era" for the Chargers.
For the Cardinals, head coach Mike LaFleur is hopeful that rookie running back Jeremiyah Love will make his NFL debut. Love, 21, sustained a high ankle sprain during a preseason game against the Raiders. If Love is unable to play, backups Tyler Allegier and Bam Knight are expected to handle the majority of carries. Key players Trey McBride, Marvin Harrison Jr., and Michael Wilson are slated to participate in the game.
Fans without cable can stream the game for free via a five-day trial of DIRECTV, which includes CBS in its programming. The Choice plan is recommended for access to over 125 channels.