The Keir Starmer government has experienced a rapid pace of senior departures this autumn, with Labour’s former cabinet minister Lord Mandelson sacked as the UK's ambassador to the United States after the emergence of emails linking him to Jeffrey Epstein.

Political editor Chris Mason said the attrition of senior figures is running “at one a week”, a pattern underlined by the high-profile exit of Deputy Prime Minister Angela Rayner earlier in the autumn and the latest removal of Mandelson. Downing Street said it had not previously been aware of the “depth and extent” of Mandelson’s relationship with Epstein and that the material revealed new facts that affected his position.

The dismissal came after media reports of emails in which Mandelson is said to have urged Epstein to "fight for early release". The Sun reported the exchange; the BBC said Mandelson disputes the claim that he believed Epstein’s first conviction was wrongful, and that he instead privately supported a friend, believed he was telling the truth and thought the sentence length should be challenged. Mandelson has not contested that he was in touch with Epstein.

The revelations prompted swift criticism from ministers. Mike Tapp, a Home Office minister appointed last week, told BBC Radio 4 he was left to “shudder” by the emails and that they “leave a bad taste in the mouth”. Health Secretary Wes Streeting said he was "completely disgusted" by what he had heard. The Foreign Office announced Mandelson's removal shortly before 11 a.m. as an urgent Commons question on the matter was being answered.

Mandelson's departure marks the third time the veteran Labour politician has left a high-profile government role. He resigned as trade and industry secretary in 1998 after a controversy over a loan and stepped down as Northern Ireland secretary in 2001 amid scrutiny over the handling of a passport application.

Sir Keir Starmer now faces questions about what he and his office knew of Mandelson’s relationship with Epstein and whether further scrutiny should have taken place before the ambassadorial appointment. Officials at the Foreign Office and Downing Street have begun searching for a replacement for the Washington post with urgency, noting the proximity of next week’s state visit by US President Donald Trump.

Names reported to be under consideration include Dame Karen Pierce, who previously served as ambassador to the United States until February and is seen by some as able to restore continuity; Richard Moore, the outgoing head of MI6; and Lord Sedwill, a former cabinet secretary. Government sources said there was a case for a quick appointment given the diplomatic sensitivities and the disruption in recent days.

The sequence of departures has fueled broader political debate over ministerial vetting and the durability of Starmer’s leadership under sustained scrutiny. Critics argue the government should have been more probing when appointing senior figures; supporters say rapid action once new information emerged showed accountability.

Mandelson’s removal and the earlier resignation of Rayner have compounded a turbulent period for the administration, which now confronts both the immediate task of filling a key ambassadorial post and the longer-term political challenge of stabilising its senior team ahead of high-profile international engagements.