Images taken as President Donald Trump and First Lady Melania Trump departed Washington for a three-day state visit to the United Kingdom show what appears to be a patch of makeup on the president’s right hand, renewing online speculation about his health just days before ceremonial events with King Charles.

The photographs, released as the president flew to Windsor Castle on Tuesday evening, follow weeks in which observers pointed to bruising and other marks on Trump’s hands and lower legs. The White House has said those findings are consistent with a diagnosis of chronic venous insufficiency and with irritation from frequent handshaking and the use of aspirin.

When asked about the photographs, the White House redirected inquiries to statements from the president’s physician, Dr. Sean Barbabella, and former White House physician Rep. Ronny Jackson. "Recent photos of the President have shown minor bruising on the back of his hand," Dr. Barbabella said. "This is consistent with minor soft tissue irritation from frequent handshaking and the use of aspirin, which is taken as part of a standard cardiovascular prevention regimen."

Jackson, who served as White House physician under three administrations, said in a separate statement that he could "tell you unequivocally: President Donald J. Trump is the healthiest president this nation has ever seen."

White House press secretary Karoline Leavitt has previously said the president noticed mild swelling in his lower legs in July and was evaluated by the White House medical unit. Leavitt said the evaluation included diagnostic vascular studies and bilateral lower-extremity ultrasounds that showed chronic venous insufficiency, a common condition in people older than 70. She said there was no evidence of deep vein thrombosis or arterial disease and that "the president remains in excellent health."

Despite those official statements, posts on social media have circulated a range of theories, including unverified claims that the markings are signs of cancer or other serious illness. Those suggestions have not been supported by medical evidence released by the White House and remain unsubstantiated.

Photographs and footage over recent months have drawn attention to the president's hands and gait. In August, a sizeable bruise on Trump’s right hand was visible during an Oval Office meeting with South Korean President Lee Jae Myung. Images from a golf outing surfaced showing similar marks, and a video from March prompted discussion after it appeared to show the president dragging his right leg on a course.

As Trump arrived in the U.K., security preparations were heightened around Windsor Castle. British police described a 24-hour policing operation in the area, including armed response units and baton-equipped officers, after declaring a "very high threat level" for events tied to the visit. Demonstrations were expected on the high street in Windsor on Tuesday night, with organizers from the Stop Trump Coalition planning protests.

Trump and the first lady are scheduled to be hosted by King Charles during the state visit, which will include a ceremonial welcome and a state banquet. Speaking as he left the White House on Tuesday, Trump said U.K. officials had indicated they wanted to continue trade negotiations during the trip.

The White House has pointed to the president’s April physical at Walter Reed National Military Medical Center, conducted by Dr. Barbabella, as evidence of his overall fitness. The administration released a range of test results from that exam, which it said included extensive testing and a cognitive assessment.

Reporting and commentary about the president’s appearance and health have continued to circulate in U.S. and international media and on social platforms as the state visit proceeds. The White House has continued to cite medical statements to address public questions about the president’s condition.