express gazette logo
The Express Gazette
Monday, September 28, 2026

The Slimming Pill You Might Have Forgotten

Experts suggest an older, cheaper drug could offer benefits similar to newer weight-loss medications like Mounjaro, particularly for individuals struggling with binge eating or cravings.

US Politics • 2 hours ago
The Slimming Pill You Might Have Forgotten

While newer weight-loss medications like Wegovy and Mounjaro have gained significant attention, often associated with celebrity endorsements, experts are highlighting the potential of an older, less-discussed drug. This medication is noted for its efficacy, especially for individuals who experience binge eating or persistent cravings.

The drug in question, phentermine, has been available for decades. Unlike some of the newer, more expensive options, phentermine is often more affordable. Its mechanism of action is believed to involve suppressing appetite, which can lead to reduced calorie intake and subsequent weight loss. This is particularly beneficial for those who find it challenging to manage their eating habits due to frequent cravings or episodes of binge eating.

Phentermine works by stimulating the central nervous system, which can increase heart rate and blood pressure, and decrease appetite. It is typically prescribed for short-term use as part of a comprehensive weight-loss program that includes diet and exercise. However, its long history means that its side effect profile and potential interactions are relatively well-understood compared to newer drugs.

Weight-loss drugs have become a prominent topic, with public figures like Oprah Winfrey openly discussing their use of medications such as Mounjaro. This has brought the broader category of weight-management pharmaceuticals into the spotlight. While the newer drugs often function by mimicking gut hormones to regulate appetite and slow digestion, phentermine offers a different approach through its stimulant properties.

Experts emphasize that any weight-loss medication should be used under the guidance of a healthcare professional. They can assess individual health conditions, potential risks, and determine the most appropriate treatment plan. The discussion around phentermine suggests a renewed look at established treatments that may provide effective and cost-efficient alternatives in the ongoing pursuit of weight management.


Sources