Flea-Borne Typhus Outbreak Hospitalizes Six in Los Angeles

Six people have been hospitalized in a new outbreak of flea-borne typhus in Los Angeles, with health officials investigating the cluster in the Wilshire Center area. This latest outbreak follows a similar one earlier this year in Pico-Union, where five individuals were hospitalized.

Health authorities believe fleas are the primary source of transmission for the current outbreak. Flea-borne typhus, a bacterial infection caused by Rickettsia typhi, is historically associated with areas of poor sanitation and is commonly linked to fleas carried by rats and other animals. An infectious disease specialist noted that contact with fleas is the major exposure route, and cases often appear in areas with inadequate sanitation, as well as around homeless encampments. Outdoor pets can also encounter infected fleas.

Infection occurs when feces from an infected flea enter the body through broken skin or the eyes. Symptoms, which typically appear within one to two weeks, can include fever, headache, vomiting, rash, muscle soreness, and body aches. The disease is not contagious between people and can be treated with antibiotics if diagnosed early.

The Wilshire Center outbreak coincides with a rising trend of flea-borne typhus cases in Los Angeles County. The county recorded a record 220 cases in 2025, with nearly 90% of those diagnosed requiring hospitalization. So far this year, 109 cases have been reported.

County health officials have previously advised that infected fleas can be carried by various animals, including rats, stray cats, and opossums. Exposure can occur within residential areas without individuals realizing an animal is carrying infected fleas. Residents are advised to maintain year-round flea control for pets, avoid contact with wild or stray animals, and take measures to prevent rodents and other wildlife from inhabiting their properties.