Leading experts in cancer research gathered at the TIME100 Health Leadership Forum in New York to discuss significant advancements in the fight against cancer, alongside the ongoing work toward finding a cure. Resources, including philanthropic investments and federal funding, have been crucial in enabling scientists and oncologists to achieve the current progress in cancer prevention and treatment, according to Shane Jacobson, CEO of the American Cancer Society and the American Cancer Society Cancer Action Network.

Cancer remains a widespread disease, with approximately one in three men and women in the U.S. expected to receive a diagnosis in their lifetime, Jacobson noted. He described the disease as historically devastating due to a limited understanding, which has spurred the allocation of necessary resources for its tackle.

Recent developments, such as the promising results of an mRNA cancer vaccine announced by Moderna and Merck, are the culmination of decades of research, knowledge, and learning from failures, Jacobson explained. The pace of innovation has accelerated, with significant breakthroughs now occurring on a near-monthly basis. However, he stressed that equitable access to these new drugs and therapies is as important as the innovations themselves, to ensure they reach their full potential.

Vaccines and immunotherapy are emerging as powerful tools, harnessing the immune system to combat cancer, said Dr. Andrea Cercek, a gastrointestinal medical oncologist at Memorial Sloan Kettering Cancer Center and a TIME100 Health honoree. This approach aims to equip the immune system to recognize and fight foreign entities.

Cercek shared findings from a study where patients with a specific type of rectal cancer treated with an immunotherapy drug for six months showed no detectable tumors and did not require subsequent chemotherapy, radiation, or surgery. She indicated that this type of treatment is close to being applied successfully to other cancer types, potentially reducing the need for more invasive therapies.

When asked if cancer will be cured, Cercek expressed certainty, suggesting that early detection and prevention will ultimately be the keys to a cure. Jacobson echoed this sentiment, adding that the future will likely see multiple cures rather than a single one, a trend already becoming apparent.