Actress Busy Philipps, known for her role as Audrey Liddell in the late 1990s drama "Dawson's Creek," revealed she was diagnosed with a rare brain tumor in February. The diagnosis came shortly after the death of her former co-star, James Van Der Beek, who died in February at age 48 from colorectal cancer.

Philipps, 47, stated she underwent surgery in early March to remove a 2.6-centimeter tumor. She was diagnosed with a grade 2 oligodendroglioma, a slow-growing tumor, after undergoing a full-body MRI scan. The scan was prompted after she was inspired to get checked following Van Der Beek's death. Despite initially considering canceling her appointment due to grief, her ex-husband encouraged her to proceed, saying Van Der Beek would have wanted her to prioritize her health. The tumor was found to be malignant, though her doctor indicated it has a favorable prognosis among malignant gliomas.

Philipps experienced a setback in April when she contracted a staphylococcus infection at her incision site, requiring a second surgery. She described the experience as feeling like she was back at square one.

A History of Hardship for the "Dawson's Creek" Cast

The personal lives of the "Dawson's Creek" cast have been marked by significant challenges in the two decades since the show concluded in 2003. The series, which launched the careers of Katie Holmes, Michelle Williams, Joshua Jackson, and James Van Der Beek, followed the lives of high school students in Capeside.

James Van Der Beek, who played the titular character Dawson Leery, passed away after a private battle with colorectal cancer. He is survived by his wife, Kimberly, and their six children. Before his death, Van Der Beek had stepped away from the spotlight, moving his family to a ranch in Texas in 2020 for a simpler life.

Michelle Williams, who portrayed Jen Lindley, has achieved significant critical acclaim, earning four Oscar nominations and two Golden Globe awards. Her personal life was deeply affected by the tragic death of her partner, Heath Ledger, in 2008, just months after the birth of their daughter, Matilda. Ledger died from an accidental drug overdose at age 28. Williams has spoken about the profound loss for her daughter, stating that it "just won’t ever be right" that Matilda does not have her father.

Joshua Jackson, who played Pacey Witter, has continued to find success in television, starring in series like "Fringe" and "Doctor Odyssey." Jackson's personal life has also seen difficulties, including a recent divorce filing from his wife, Jodie Turner-Smith, citing irreconcilable differences. They are currently navigating custody arrangements for their young daughter. Additionally, Jackson lost his $2 million home in Topanga Canyon to wildfires the previous year, a property that held sentimental value as it was where he lived as a child.

Katie Holmes, who played Joey Potter, experienced a highly publicized divorce from actor Tom Cruise in 2012 after five years of marriage. The settlement granted Holmes sole custody of their daughter, Suri. Holmes has spoken about the challenges of raising Suri, particularly in navigating her daughter's need for privacy. She has since focused on directing and acting, with her latest project, "Happy Hours," reuniting her with Joshua Jackson.

Actor Obi Ndefo, who played Bodie Wells, died in November 2024 at the age of 51. His death followed a severe car accident in 2019 that resulted in the amputation of both his legs. Ndefo was struck by a drunk driver while loading groceries. A GoFundMe campaign was established to help with his medical expenses and home modifications.

Heidi Ferrer, a writer for "Dawson's Creek," died by suicide in 2021 after a prolonged battle with COVID-19. Her husband reported that she had been bedridden with severe pain and neurological issues for 13 months. He indicated that she felt her condition was worsening and that medical diagnoses and treatment referrals were significantly delayed.