Bills and Lions Kick Off Week 2 of Thursday Night Football on Prime Video

The Buffalo Bills are set to host the Detroit Lions for Thursday Night Football at Highmark Stadium, marking the second week of the NFL season. Kickoff is scheduled for 8:15 p.m. ET.

This matchup features two teams that secured opening week victories. The Lions narrowly defeated the New Orleans Saints in overtime with a final score of 31-30, thanks in part to Jahmyr Gibbs's 156 rushing yards and two touchdowns. The Bills also faced a close contest, defeating the Houston Texans 36-31. Josh Allen contributed 334 passing yards and two touchdowns, with Dalton Kincaid and DJ Moore combining for 230 receiving yards.

Fans can watch tonight's game live on Prime Video. For those without a Prime Video subscription, a 30-day free trial of Amazon Prime is available, which includes Prime Video streaming services, free two-day shipping, and other perks. Following the trial period, Amazon Prime costs $14.99 per month or $139 annually. A discounted "Prime for Young Adults" membership is also available for individuals aged 18 to 24, offering a six-month free trial followed by a 50% discount on the monthly price.

Alternatively, the game can be streamed on mobile devices via NFL+. The broadcast is part of Amazon's coverage of Thursday Night Football for the 2026 season. Following this game, the NFL schedule on Prime Video continues with matchups including the Atlanta Falcons at Green Bay Packers on September 24 and the Pittsburgh Steelers at Cleveland Browns on October 1.