Reigning UFC welterweight champion Islam Makhachev will make his first title defense of the year on Saturday night against Ian Machado Garry in the main event of UFC 330. The fight marks Makhachev's first defense of the 170-pound title following his victory over Jack Della Maddalena in November.

Makhachev, who holds a 14-fight winning streak, will face Garry in the octagon at Xfinity Mobile Arena in Philadelphia. The full card for UFC 330 includes 12 fights, with the main card scheduled to begin at 9 p.m. ET and be available on Paramount+.

For those looking to bet on the event, the fight offers various betting options, including moneyline bets and prop bets. The moneyline wager focuses on predicting the winner of the fight. Makhachev is the favorite at -340 odds, while Garry is the underdog at +270.

Another betting option is the over/under on the total number of rounds. The UFC 330 main event has an over/under set at 4.5 rounds. Bettors can wager on whether the fight will end before or after the 1 minute and 30-second mark of the fourth round. The odds for the over (fight goes longer than 4.5 rounds) are -180, and for the under (fight lasts less than 4.5 rounds) are +140.

Prop bets offer additional ways to wager on the fight, covering aspects such as significant strikes landed, the method of victory (e.g., knockout, submission, decision), or whether the fight will go the distance. The variety of prop bets can differ among sportsbooks.

This championship bout is one of two title fights on the UFC 330 card, both of which are expected to draw significant attention from bettors and fans. Title fights often feature highly motivated competitors and can be unpredictable, with outcomes potentially decided by a single impactful moment.