Scottie Scheffler and Rory McIlroy are set as co-favorites with odds of +750 for the 154th Open Championship, scheduled to begin Thursday at Royal Birkdale Golf Club in Southport, England. McIlroy enters the tournament following a seventh-place finish at the Genesis Scottish Open, his fourth top-10 performance in 10 events in 2026, including a win at Augusta.

Scheffler, who missed the cut at the Renaissance Club last week, had his streak of 78 consecutive tournaments making the cut broken. He had been the favorite or co-favorite in the last 15 majors. Both players have a notable history at the Open Championship. Scheffler is the defending champion and has achieved two other top-10 finishes in five starts. McIlroy, a former winner in 2014, has secured eight top-10 finishes in 15 Open Championship appearances since turning professional.

Hometown favorite Tommy Fleetwood, who grew up near Royal Birkdale, is listed at 15/1 odds to win his first major. Matt Fitzpatrick, hailing from Sheffield approximately 80 miles east, also has odds of 15/1.

Jon Rahm rounds out the top contenders at 22/1. Other notable golfers include Justin Rose and Chris Gotterup at 30/1, Cameron Young at 35/1, and Bryson DeChambeau at 50/1. Odds are provided by bet365 Sportsbook as of July 13.