Changes in the toes, such as numbness, tingling, or a burning sensation, can be an early and often overlooked sign of Vitamin B12 deficiency, according to health experts. This deficiency is estimated to affect around one in 10 women and is particularly common in individuals over 50, though a growing number of younger adults are also being diagnosed.

The feet are particularly susceptible to the effects of vitamin deficiency because they are at the extremity of the body's nerve and blood supply. "The feet sit at the very end of the body's nerve and blood supply, so they're the first to feel the effects when metabolism or circulation is compromised," said Marion Yau, a podiatrist. "Nutrient deficiencies typically affect the longest nerves in the body first - including those running down to the toes."

Vitamin B12 is essential for producing myelin, the protective coating around nerve cells. A lack of this vitamin can lead to the breakdown of myelin, disrupting nerve signals and causing these sensations in the feet. Furthermore, a deficiency can impair the oxygen-carrying capacity of red blood cells, potentially leading to changes in foot color, persistent coldness, and slow-healing wounds.

These symptoms are often misattributed to other conditions like anxiety, menopause, or dementia. The slow onset of symptoms means many individuals may live with the deficiency for years, risking irreversible nerve damage or heart failure.

Increasing Diagnosis Rates

Recent data suggests an increase in diagnosed Vitamin B12 deficiency. In England, the number of annual prescriptions for Vitamin B12 has doubled in the last decade, rising from 2.5 million to 5 million. Experts believe that underdiagnosis is still significant, contributing to millions potentially suffering needlessly.

Other Causes of Foot Sensations

While vitamin deficiency is a primary concern, burning or numb feet can also be a symptom of uncontrolled Type 2 diabetes. This condition, where blood sugar levels become dangerously unstable, can lead to serious complications including heart disease, stroke, and dementia. High levels of uric acid, which can form crystals in the big toe joint, are also linked to an increased risk of developing Type 2 diabetes and can cause similar sensations.

Podiatrists can help manage the pain associated with these conditions, but medical advice is crucial. "That's why it is always important to discuss any changes in your feet with your GP, who will be able to test for any underlying issues," Ms. Yau advised. A GP can administer blood tests to check for both vitamin levels and glucose levels, enabling a proper diagnosis and treatment plan. Lifestyle changes, such as a healthy diet and regular exercise, are key to managing conditions like Type 2 diabetes.