Creatine monohydrate, a common supplement used to enhance athletic performance, may also hold potential as an adjunctive treatment for major depressive disorder, according to a recent systematic review. The review, which analyzed existing research, suggested that creatine could help as an add-on therapy for individuals experiencing depression.
However, the researchers emphasized that the evidence is mixed and further investigation is needed to confirm these potential benefits. The study did not indicate that creatine is a standalone treatment for depression but rather a possible supplementary option.
Major depressive disorder is a serious mood disorder that affects how a person feels, thinks, and behaves and can lead to a variety of emotional and physical problems. While standard treatments include therapy and medication, research into alternative and complementary therapies is ongoing.